A randomly generated, totally novel enzyme rescues mutant bacteria

Enlarge / Colorized scanning electron micrograph of Escherichia coli (E. coli), grown in culture and adhered to a cover slip. (credit: NIAID / Flickr) Proteins are chains of amino acids, and each link in the chain can hold any one of the 20 amino acids that life relies on. If you were to pick each […]

We may now be able to engineer the most important lousy enzyme on the planet

Enlarge / To genetically engineer RuBisCo, we’ll no longer need all the time and space involved with these plants. (credit: Roy Kaltschmidt) The single most abundant protein on the planet isn’t actually very good at its job. And, unfortunately, its job is important: to pull carbon dioxide out of the atmosphere and incorporate it into […]

Researchers find an enzyme that harvests light to make hydrocarbons

Enlarge / FAD, the key ingredient to making this system work. The bit that absorbs blue light is on the right. (credit: Wikimedia Commons) It’s pretty easy to grow vast quantities of microbes. It’s a lot harder to convert those microbes into something useful. For example, we’ve engineered algae that, when starved for nitrogen, will […]

Obesity pill 'on horizon' after enzyme that tells brain when its full is discovered

The chemical enzyme is sent by fat cells as a sensor to indicate enough food has been eaten. This stops any more eating – preventing us from putting on too much weight. The breakthrough could could also lead to treatments for eating disorders such as anorexia nervosa. Drugs that target the protein known as BH4 […]