Liverpool host Manchester United at Anfield on Saturday October 14 – just two days after Coutinho and Firmino arrive back from Brazil duty.
And The Metro claim Liverpool could be without the Brazilian duo against United as they may struggle to be 100 per cent fit.
Both Coutinho and Firmino are expected to face Chile in Brazil’s final World Cup qualifier, which finishes in the early hours of Wednesday morning in Sao Paulo.
The pair will then return back to England in a private jet immediately after the game.
Liverpool boss Jurgen Klopp will be desperate to have the duo available against the Red Devils as he looks to get their title race back on track.
The Reds have fallen seven points behind Premier League table-toppers Manchester City and United, who are just behind on goal difference.
Coutinho has been in top form after missing Liverpool’s opening six games of the season with a back injury, scoring three goals and providing one assist in six outings.
And despite Firmino’s form dipping in recent weeks, the striker has still contributed to seven goals for Klopp’s side this season.