The April 2018 update for Windows 10 is now being blocked from installing on systems with certain Intel SSDs.
With the update installed, systems with the Intel SSD 600p Series and Intel SSD Pro 6000p Series devices seem to crash repeatedly during startup. The problem appears to be recoverable insofar as you can hold down F8 and roll back the update. But that’s the only known solution at the time of writing. The issue appears to be unique to Intel’s firmware on the SSD; other devices with the same controllers (but different firmware) do not seem to be having any problems.
Microsoft is now blocking the update from affected systems until a solution is devised.