The Loose Women presenter was struggling to beat the Chaser Mark Labbett – also known as the Beast – when she suddenly revealed to Walsh that she needed the bathroom during a particularly stressful question about the size of birds.
“Come on Bradley, I need a wee now,” she told him, hopping up and down.
While the comedian seemed shocked by her outburst, he didn’t react at first.
The Celebrity Big Brother star managed to hold it together as the presenter refused to tell her if she’d gotten the question right.
“If I’ve got this right I’m going to give you the biggest hug,” she told him.
But Walsh snapped back at that point, saying: “Not if you’re gonna wet yourself you’re not.”
Khan burst out laughing along with the audience at that point, and the result was eventually revealed that she’d incorrectly picked a starling as the biggest bird rather than a blackbird.
Disappointed, she begged: “Oh, can I have another go, please,” to which the show’s host obviously said no.
While the 47-year-old made a number of mistakes on her attempt at the iconic quiz show, she also revealed that she had feelings for the grumpy Chaser.
“Can I just say, I actually find you very attractive. I like a bit of an intelligent man, just so you know,” she giggled.
But The Beast didn’t take the contestant’s compliments kindly, as his only response was: “We’re both on the money show, but tonight we’re on the no money show.”