The condition is a hormonal disorder caused by prolonged exposure to the hormone cortisol – which can be caused by taking steroids.
Other people develop Cushing’s syndrome because their bodies produce too much cortisol.
It is most common in adults aged between 20 and 50 although women are almost three time as likely to be diagnosed.
While the condition is rare and only affects around one in every 50,000 people – the syndrome can affect people with type 2 diabetes, obese and have poorly controlled blood sugar levels.
The condition is also more common in people with high blood pressure.
Cushing’s syndrome – also called hypercortisolism – can cause a number of symptoms.
These can include:
Weight gain
Thinning skin which can bruise easily
Reddish-purple stretch marks on the arms, legs, breasts, thighs, stomach and buttocks
It can also cause the face to become rounder – causing fat to deposit on the face
Muscle or bone weakness is also a sign of the condition
A loss of libido – decreased interest in sex – is also a symptom
However, other symptoms can include excess hair on the face, irregular periods, severe fatigue, high blood pressure, high blood sugar irritability or depression and even a fatty deposit between the shoulders.
The National Institute of Diabetes and Digestive and Kidney Diseases said: “Metabolic syndrome – a combination of problems that includes excess weight around the waist, high blood pressure, abnormal levels of cholesterol and triglycerides in the blood, and insulin resistance-also mimics the symptoms of Cushing’s syndrome.”
Cushing’s syndrome often develops as a side effect of treatment with corticosteroids.
Corticosteroids are widely used to reduce inflammation and treat autoimmune conditions – where the immune system malfunctions and attacks healthy tissue – such as rheumatoid arthritis, Crohn’s disease and lupus.
However, the condition can be hard to diagnose because of the similarity to high blood pressure.
To diagnose the disease, patients will usually need to have a saliva test, urine test and blood test to measure cortisol levels in the body.
To treat the condition, patients will usually have to decrease the levels of steroids they are taking.
However, there are complications if the condition is left untreated.
It can lead to high blood pressure and increase the risk of heart disease and stroke.