The comedian is on course to land his professional dance partner Oti Mabuse, 30, her second consecutive win.
Not far off his heels is chart-topper HRVY, 21, who stands in good stead to secure Janette Manrara, 37, her first-ever win at 7/4.
EastEnders actress and Charles’ former co-star Maisie Smith, 19, seems to be holding the third position at 6/1.
Coral spokesperson John Hill said: “Bill is the one to beat this weekend. He has been the favourite to lift the Glitterball Trophy from early into this series.
“HRVY is sure to throw down a strong challenger to the favourite in what should be one of the best Strictly finals we have seen in recent years.”