Gene editing crunches an organism’s genome into single, giant DNA molecule

Enlarge / Individual chromosomes (right) have a complex organization when packed inside a cell’s nucleus (left). (credit: Thomas Ried/NIH) Complex organisms have complex genomes. While bacteria and archaea keep all of their genes on a single loop of DNA, humans scatter them across 23 large DNA molecules called chromosomes; chromosome counts range from a single […]

Scientists may be able to discover new drugs by ‘challenging’ organisms with clusters of random chemistry

Thomson Reuters I was cutting my grass when the battery in my iPod died. Instead of enjoying the distraction of music, my brain switched to its usual nerd mode of thinking about molecules. Within a few passes of cut grass, I was pondering the biggest “Why not?” of my scientific career: Could we discover new […]