Blair first appeared on the Australian soap back in 2001 before leaving the show in 2006.
Viewers will most likely remember the character for his friendship with Toadie Rebecchi and Connor O’Neill, who he lived with at Number 30, which was known at the time as “The House of Trouser”.
The mechanic-turned-policeman made an on-screen departure from the soap, when he moved to Oakey with fellow neighbours Angie (Lesley Baker) and Kevin Rebecca (Don Bridges).
In an interview with TV WEEK, Neighbours’ executive producer Jason Herbison revealed that Stuart will be returning to Erinsborough in a future episode, where he will “reconnect with an old friend”.
And while further details about the guest appearance are being kept top secret, Stuart will return to the Melbourne neighbourhood for a celebration involving another Ramsay Street star.
Speaking back in 2012 about the idea of reprising his Ramsay Street role, Blair said: “I did actually float the idea of Stu making a return to the Neighbours producers.
“They were too far down the path with the storyline at that point, though.
“Neighbours was my university! I didn’t go to uni or get the chance to do all those crazy things as a kid, so that’s what Neighbours was for me.”
Blair, 36, most recently starred in Australian soap Home and Away, where fans may recognise him for playing Alan Ellis, the father of the late Beth Ellis.
The Melburnian actor has also appeared on a number of reality TV shows, including the first season of Big Brother Australia – where he lost out to winner Ben Williams.
Neighbours returns to Channel 5 on Monday at 1.45pm and 5.30pm.