Kane was the Wembley hero as he scored twice after Spurs had gone behind when Luuk de Jong shocked the home side after only SIXTY TWO seconds.
Spurs were heading out of the Champions league with just 12 minutes left on the clock, but their talisman pulled one back with a scrappy effort and completed the comeback in the 89th minute.
And the England striker said he was pleased to make amends after suffering defeat in the reverse fixture back in Eindhoven.
“We said we were disappointed coming away from there,” Kane said.
“Today it wasn’t ideal conceding early but then we were dominant and created chances.
“We could have been more clinical but we’ll just take a win in the Champions League. We had to dig deep and find another level when it mattered.
“We have been grinding results out here and there all season. We are getting wins. Today was one of our best performances of the season.”
Spurs were stunned into action after De Jong rose highest to head past Gazzaniga and silence the home crowd in the second minute.
Mauricio Pochettino’s side responded well but were frustrated by the excellent Jeroen Zoet in the PSV goal.
The Dutchman pulled of a brilliant double-save in the first half to deny Christian Eriksen and then Dele Alli, who was making his return to the side after injury.
Spurs dominated possession but struggled to find a way past Zoet until Kane eventually did on 78 minutes.
A long ball forward found substitute Fernando Llorente and the Spaniard perfectly cushioned it into Kane’s path.
Kane let the ball bounce once before unleashing a left-foot drive that bounced into the ground before finding the bottom corner.
Zoet was agonisingly close to the equaliser but there was nothing he could do about the fortunate winner.
Full-back Ben Davies looped a cross over from the left-wing and Kane rose highest to head home via deflections off TWO PSV defenders on its way in.
They played out a 1-1 draw at the San Siro on Tuesday.
Spurs stay third in Group B – three points behind second-placed Inter and a further three behind Barca.
And Pochettino was quick to praise his players for keeping them in with a shout of making the last 16.
“It was a tough game. We played very good and created a lot of chances. We took a risk in the second half,” the Spurs boss said.
“The team deserved the victory. We won and suffered a lot.
“It was a massive effort so I was pleased. We play a lot in eight days. Now we need to try to recover for Saturday [at Crystal Palace].
“It is another must-win game. We are confident. This team is growing up. The team is fighting so I am so happy.
“We tried to fight. We have the character of never giving up which is so important. I am happy always with the situation.
“Today we kept pushing and that victory is so important.”